alaabta
Tayada Sare L-Glutathione La dhimay CAS 70-18-8 ee Daryeelka Maqaarka Glutathione
Faahfaahinta alaabta
MF: C10H17N3O6S
MW: 307.32
CAS: 70-18-8
1.Glutathione waa xayndaab tripeptide ah oo lagu ururiyo glutamic acid, cysteine iyo glycine iyada oo loo marayo bonds peptide.Waa mercaptan molecular hooseeya ee ugu muhiimsan unugyada naasleyda ee hoos yimaada cadaadiska antioxidant.
2.Glutathione (GSH) waa xayndaab tripeptide ah oo ay sameeyeen uumi glutamic acid, cysteine iyo glycine iyada oo loo marayo bonds peptide.Magaceeda kiimikaad waa γ- Qaabka qaabdhismeedka l-glutamyl-l-cysteyl-glycine waxa lagu muujiyey jaantuska 1-aad ee kimikalka.Marka loo eego qaabka qaabdhismeedka shaxanka, GSH way ka duwan tahay peptides iyo borotiinnada kale.Waxaa jira dammaanad peptide gaar ah oo ku jirta molecule-keeda, kaas oo ka samaysan glutamic acid γ-Carboxyl (-COOH) iyo cysteine α- Peptide bond oo ay samaysay uumi amino- (- NH2).
3.Miisaanka kelli ee glutathione waa 307.33, barta dhalaalidu waa 189 ~ 193 ℃ (kala-bax), crystal waa mid aan midab lahayn, hufan, tiir caato ah, iyo barta isoelectric waa 5.93.Waxay ku milmi kartaa biyaha, khamiirka khamriga, dareeraha ammonia iyo methyl formamide, laakiin aan lagu milmin khamriga, ether iyo acetone.Kaliya GSH ayaa dhaqdhaqaaqa jireed ku leh noolaha, GSSG-na waxay ciyaari kartaa hawlaheeda jireed ee muhiimka ah ka dib dhimista.GSH ma fududa in lagu kaydiyo dhaqdhaqaaqa biyaha sarreeya, waxaana loo kaydin karaa si adag muddo dheer kaliya marka hawsha biyaha la xakameeyo ka hooseeya 0.3.Daraasaduhu waxay muujiyeen in fiitamiinka ccchemicalbook-ka aqueous ee ka kooban GSH (ph3.3), sababtoo ah hoos u dhigista xooggan ee fitamiin C, GSH ee xalka ma noqon doono oxidized GSSG, laakiin xawaaraha burburka ayaa la dedejiyey;GSSG ee ku jira fiitamiin C xal aqueous looma beddeli doono GSH, iyo xasiloonida kaydinta waa mid aad u wanaagsan.Intaa waxaa dheer, GSSG ee afka laga nuugo waxaa lagu yarayn karaa GSH qaybta sare ee mindhicirka yar, iyo dusha unugyada epithelial mindhicirka yar γ- GTP (kaas oo GSH u kala qaybiya glutamic acid iyo Cys Gly) iyo dipeptidase waxay sidoo kale ciyaari kartaa jir ahaaneed oo muhiim ah. hawlaha.
4.Glutathione waxa ay si balaadhan uga jirtaa xayawaanka iyo dhirta, waxa ku jira khamiirka dubista, jeermiga qamadiga iyo beerka xoolaha waa mid aad u sareeya, ilaa 100 ~ 1000mg/100g;Waxa kale oo qani ku ah dhiiga dadka iyo xoolaha, sida 26chemicalbook ~ 34mg/100g in blood blood, 58 ~ 73mg/100g ee dhiiga digaaga, 10 ~ 15mg/100g ee dhiiga doofaarka iyo 14 ~ 22mg/100g ee dhiiga.GSH waxa kale oo laga helaa khudaar badan, baradhada iyo badarka.
Codsiga
1.Glutathione la dhimay waa peptide molecule yar, kaas oo ka jira tiro aad u badan noolaha, gaar ahaan unugyada beerka.Waxay ilaalin kartaa xuubka unugyada beerka, waxay kor u qaaddaa dhaqdhaqaaqa enzyme beerka, waxayna ku dari kartaa kiimikooyin badan oo sun ah oo ku jira buugga kiimikada si ay sunta uga saarto.Waxay saameyn wanaagsan ku leedahay dhaawaca beerka, cirrhosis beerka iyo cudurrada kale ee ay keento sunta daroogada, khamriga iyo sababo kale.
2.Waxay leedahay hawlaha antioxidation, xoqin xagjirrada xorta ah, sun-saarista, kor u qaadida difaaca, daahitaanka gabowga, kansarka ka hortagga, waxyeellada shucaaca iyo wixii la mid ah.
3.Reagents biochemical iyo antidotes waxaa inta badan loo isticmaalaa sumaynta biraha culus, acrylonitrile, fluoride, carbon monoxide iyo dareerayaasha organic.
4.Endogenous antioxidants kuwaas oo door muhiim ah ka ciyaara yaraynta noocyada ogsijiinta falcelinta ee la sameeyay inta lagu jiro dheef-shiid kiimikaadka unugyada iyo neefsashada degdega ah.Glutathione-S-transferase waxay kicisaa samaynta glutathione sulfide oo leh xenobiotics, leukotrienes iyo molecules kale oo leh xarumaha korantada.Glutathione sidoo kale waxay samaysaa xidhidhyo disulfide ah oo leh hadhaaga cysteine ee borotiinada.Iyadoo loo marayo hababkan, waxay yeelan kartaa saameyn la yaab leh oo lagu dhimayo waxtarka wakiilada ka hortagga kansarka.
